https://siyuanj.github.io/blog/ https://siyuanj.github.io/ https://siyuanj.github.io/note/ https://siyuanj.github.io/publications/ https://siyuanj.github.io/blogs/2025-12-10-metalloproteases_design.html2025-12-10 https://siyuanj.github.io/blogs/2026-08-28-nacraft_aptamer_design-zh.html2026-08-28 https://siyuanj.github.io/blogs/2026-08-28-nacraft_aptamer_design.html2026-08-28 https://siyuanj.github.io/blogs/2026-08-28-rna_pseudoknot_design-zh.html2026-08-28 https://siyuanj.github.io/blogs/2026-08-28-rna_pseudoknot_design.html2026-08-28 https://siyuanj.github.io/blogs/2026-08-29-odesign_world_model-zh.html2026-08-29 https://siyuanj.github.io/blogs/2026-08-29-odesign_world_model.html2026-08-29 https://siyuanj.github.io/blogs/2026-08-30-flashbind_virtual_screening-zh.html2026-08-30 https://siyuanj.github.io/blogs/2026-08-30-flashbind_virtual_screening.html2026-08-30 https://siyuanj.github.io/blogs/2026-08-30-minifold-zh.html2026-08-30 https://siyuanj.github.io/blogs/2026-08-30-minifold.html2026-08-30 https://siyuanj.github.io/blogs/2026-08-30-siteaf3-zh.html2026-08-30 https://siyuanj.github.io/blogs/2026-08-30-siteaf3.html2026-08-30 https://siyuanj.github.io/blogs/2026-09-01-alphainterp_af3-zh.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-alphainterp_af3.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-bish_bash_fold-zh.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-bish_bash_fold.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-interplm_sparse_autoencoder-zh.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-interplm_sparse_autoencoder.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-probing_steering_boltz-zh.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-probing_steering_boltz.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-two_stages_folding-zh.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-01-two_stages_folding.html2026-09-01 https://siyuanj.github.io/blogs/2026-09-02-aftoolkit_alphafold_representations-zh.html2026-09-02 https://siyuanj.github.io/blogs/2026-09-02-aftoolkit_alphafold_representations.html2026-09-02 https://siyuanj.github.io/blogs/2026-09-03-binder_design_developability-zh.html2026-09-03 https://siyuanj.github.io/blogs/2026-09-03-binder_design_developability.html2026-09-03 https://siyuanj.github.io/blogs/2026-09-04-cross_graph_rna_design-zh.html2026-09-04 https://siyuanj.github.io/blogs/2026-09-04-cross_graph_rna_design.html2026-09-04 https://siyuanj.github.io/blogs/2026-09-05-boltz1_biomolecular_interaction-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-boltz1_biomolecular_interaction.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-boltz2_binding_affinity-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-boltz2_binding_affinity.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-pair_repr_scaling-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-pair_repr_scaling.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-restrain_distance_injection-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-restrain_distance_injection.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-rfdiffusion1_protein_design-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-rfdiffusion1_protein_design.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-rfdiffusion2_enzyme_scaffolding-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-rfdiffusion2_enzyme_scaffolding.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-rfdiffusion3_allatom_interactions-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-rfdiffusion3_allatom_interactions.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-switchcraft_state_switching-zh.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-05-switchcraft_state_switching.html2026-09-05 https://siyuanj.github.io/blogs/2026-09-06-rhofold_rna_3d_structure-zh.html2026-09-06 https://siyuanj.github.io/blogs/2026-09-06-rhofold_rna_3d_structure.html2026-09-06 https://siyuanj.github.io/blogs/2026-09-07-slow_modes_allosteric_sites-zh.html2026-09-07 https://siyuanj.github.io/blogs/2026-09-07-slow_modes_allosteric_sites.html2026-09-07 https://siyuanj.github.io/blogs/2026-09-08-af2bind_binding_sites-zh.html2026-09-08 https://siyuanj.github.io/blogs/2026-09-08-af2bind_binding_sites.html2026-09-08 https://siyuanj.github.io/blogs/2026-09-10-aptamer_complex_prediction_benchmark-zh.html2026-09-10 https://siyuanj.github.io/blogs/2026-09-10-aptamer_complex_prediction_benchmark.html2026-09-10 https://siyuanj.github.io/blogs/2026-09-11-la_proteina_atomistic_generation-zh.html2026-09-11 https://siyuanj.github.io/blogs/2026-09-11-la_proteina_atomistic_generation.html2026-09-11 https://siyuanj.github.io/blogs/2026-09-12-alphafold3_biomolecular_interactions-zh.html2026-09-12 https://siyuanj.github.io/blogs/2026-09-12-alphafold3_biomolecular_interactions.html2026-09-12 https://siyuanj.github.io/blogs/2026-09-13-boltzgen_universal_binder-zh.html2026-09-13 https://siyuanj.github.io/blogs/2026-09-13-boltzgen_universal_binder.html2026-09-13 https://siyuanj.github.io/blogs/2026-09-14-odin_multi_specific_binder-zh.html2026-09-14 https://siyuanj.github.io/blogs/2026-09-14-odin_multi_specific_binder.html2026-09-14 https://siyuanj.github.io/blogs/2026-09-15-boltzmol1_virtual_screening-zh.html2026-09-15 https://siyuanj.github.io/blogs/2026-09-15-boltzmol1_virtual_screening.html2026-09-15 https://siyuanj.github.io/blogs/2026-09-16-motion_modes_allosteric_prediction-zh.html2026-09-16 https://siyuanj.github.io/blogs/2026-09-16-motion_modes_allosteric_prediction.html2026-09-16 https://siyuanj.github.io/blogs/2026-09-17-deepssinter_contact_prediction-zh.html2026-09-17 https://siyuanj.github.io/blogs/2026-09-17-deepssinter_contact_prediction.html2026-09-17 https://siyuanj.github.io/blogs/2026-09-18-ambient_proteins_low_quality_structures-zh.html2026-09-18 https://siyuanj.github.io/blogs/2026-09-18-ambient_proteins_low_quality_structures.html2026-09-18 https://siyuanj.github.io/blogs/2026-09-19-rfoptimization_design_optimization-zh.html2026-09-19 https://siyuanj.github.io/blogs/2026-09-19-rfoptimization_design_optimization.html2026-09-19 https://siyuanj.github.io/blogs/2026-09-20-coevolution_allosteric_residues-zh.html2026-09-20 https://siyuanj.github.io/blogs/2026-09-20-coevolution_allosteric_residues.html2026-09-20 https://siyuanj.github.io/blogs/2026-09-21-rna_aptamer_generative_design-zh.html2026-09-21 https://siyuanj.github.io/blogs/2026-09-21-rna_aptamer_generative_design.html2026-09-21 https://siyuanj.github.io/blogs/2026-09-22-allosteric_site_seq_struct_prediction-zh.html2026-09-22 https://siyuanj.github.io/blogs/2026-09-22-allosteric_site_seq_struct_prediction.html2026-09-22 https://siyuanj.github.io/blogs/2026-09-23-boltzdesign1_binder_design-zh.html2026-09-23 https://siyuanj.github.io/blogs/2026-09-23-boltzdesign1_binder_design.html2026-09-23 https://siyuanj.github.io/blogs/2026-09-24-proteinmpnn_sequence_design-zh.html2026-09-24 https://siyuanj.github.io/blogs/2026-09-24-proteinmpnn_sequence_design.html2026-09-24 https://siyuanj.github.io/blogs/2026-09-25-autoscreen_target_discovery-zh.html2026-09-25 https://siyuanj.github.io/blogs/2026-09-25-autoscreen_target_discovery.html2026-09-25 https://siyuanj.github.io/blogs/2026-09-26-allofusion_allosteric_site_prediction-zh.html2026-09-26 https://siyuanj.github.io/blogs/2026-09-26-allofusion_allosteric_site_prediction.html2026-09-26 https://siyuanj.github.io/blogs/2026-09-27-allobench_allosteric_benchmark-zh.html2026-09-27 https://siyuanj.github.io/blogs/2026-09-27-allobench_allosteric_benchmark.html2026-09-27 https://siyuanj.github.io/blogs/2026-09-28-agentic_binder_campaign-zh.html2026-09-28 https://siyuanj.github.io/blogs/2026-09-28-agentic_binder_campaign.html2026-09-28 https://siyuanj.github.io/blogs/2026-09-29-protein_rna_complex_single_sequence-zh.html2026-09-29 https://siyuanj.github.io/blogs/2026-09-29-protein_rna_complex_single_sequence.html2026-09-29 https://siyuanj.github.io/blogs/2026-09-30-gpcr_exoframe_modulators-zh.html2026-09-30 https://siyuanj.github.io/blogs/2026-09-30-gpcr_exoframe_modulators.html2026-09-30 https://siyuanj.github.io/blogs/2026-10-01-na_mpnn_sequence_design-zh.html2026-10-01 https://siyuanj.github.io/blogs/2026-10-01-na_mpnn_sequence_design.html2026-10-01 https://siyuanj.github.io/blogs/2026-10-02-ae_pocketminer_cryptic_pockets-zh.html2026-10-02 https://siyuanj.github.io/blogs/2026-10-02-ae_pocketminer_cryptic_pockets.html2026-10-02 https://siyuanj.github.io/notes/2025-01-20-note_test.html2025-01-20 https://siyuanj.github.io/notes/test.html2026-10-11